Journal of Oral Tissue Engineering

ORIGINAL ARTICLE
Connective Tissue Reaction and Bone-cement Contact after Implantation of PMMA Resin Cements

Takeru MORISHITA, Tsutomu SUGAYA, Megumi NAKATSUKA, Maki SUNOSAKI and Masamitsu KAWANAMI
Department of Periodontology and Endodontology,
Division of Oral Health Science, Hokkaido University
Graduate school of Dental Medicine, Sapporo, Japan


J Oral Tissue Engin 2012;10(1):1-12

SYNOPSIS
Super Bond (SB) shows biocompatible and adhesive properties to bone as well as to dentin. In this study, SB induced minimal inflammation when implanted in connective tissue of rat, although Multibond II (MB) and Surgical Simplex®(SX) caused intense inflammatory response. SB was mostly in direct contact with bone without formation of fibrous tissue when implanted in the intramedullary canal of rat, although formation of fibrous tissue between resin cement and bone was mostly observed with MB and SX. Moreover, SEM observation revealed that SB was mostly in direct contact without a gap. Disorders of bone tissue or bone cells were not observed in the case of SB, MB and SX implanted in the intramedullary canal. Thus, 4-META/MMA-TBB cement can be effectively used as a bone cement.

Key words: 4-META/MMA-TBB resin, Bone cement, Biocompatibility, Bone, Adhesion