Journal of Oral Tissue Engineering

ORIGINAL ARTICLE
 Clinical Usage Experience and Evaluation of Application of Platelet Rich Plasma Gel in Impacted Tooth Extraction: A Preliminary Study

 Nozomu FUKUI, Takaaki UENO, Yoshihiro KIMURA, Yoichro NAKAJIMA, Akihio SUNANO, Yuichi ITO and Shin KASUYA
Division of Medicine for Function and Morphology of Sensor Organ,
Dentistry and Oral Surgery, Osaka Medical College, Osaka, Japan


J Oral Tissue Engin 2014;12(2):80-84
SYNOPSIS
The aim of this study was to investigate the safety of use of platelet rich plasma gel (PRPG) during the healing process of extracted sockets of impacted mandibular third molar in humans.
Ten patients were included in the present study. Impacted third molars were surgically extracted in the same session.
The prepared PRPG was placed into the extracted sockets. We evaluated the wound after 7 days for postoperative redness, swelling, pus discharge, pain and the panoramic radiograph for changes in bone at the surgical site. Healing was uneventful in all the cases treated with PRPG. Panoramic radiographic examination after around 6 months did not show abnormal bone formation at the surgical site.
The present study suggests that the usage of PRPG for impacted third molar extraction had no adverse effects and PRPG can be safely used in the healing process of extracted sockets.

Key words: Platelet rich plasma (PRP) Gel, extracted socket, Growth factor