Journal of Oral Tissue Engineering

Biological Safety of Mixed Acid Heat Treatment in SLM (Selective Laser Melting Technique) Titanium Mesh

Shihoko INUI1, Kayoko YAMAMOTO1, Nahoko KATO-KOGOE1, Yoichiro NAKAJIMA1, Kazuya INOUE1, Hiroyuki NAKANO1,
Seiji YAMAGUCHI2, Azumi HIRATA3, Yoichi KONDO3, and Takaaki UENO1

1Department of Dentistry and Oral Surgery, Osaka Medical College, Osaka, Japan
2Department of Biomedical Sciences, College of Life and Health Sciences, Chubu University, Japan
3Department of Anatomy and Cell Biology, Osaka Medical College, Osaka, Japan

J Oral Tissue Engin 2018; 16(1): 27-31.

A titanium (Ti) mesh using the Selective Laser Melting (SLM) technique was subjected to surface modification by mixed acid heating, and it was applied to a rat calvarial bone defect model. Safety of the mixed acid heat treatment on the surface was evaluated by investigating the inflammatory response based on macroscopic and microscopic findings. Worsening of inflammatory reactions was not observed in the SLM Ti mesh-embedded group at 2, 4 or 7 weeks. These results suggest that mixed acid and heat treatment surface modification Ti mesh is safe.

Key words: Selective Laser Melting technique, titanium mesh, mixed acid heat treatment

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